TGT a Drug Target to Study pKa Shifts, Residual Solvation & Protein-Protein Interface Formation
In this thesis multiple computer aided methods of structure based drug design along with X-ray crystallography and kinetic measurements were used to investigate inhibitors of tRNA-guanine transglycosylase (TGT) a putative target for a new specific antibiotic against Shigella bacteria. Within a year...
Wedi'i Gadw mewn:
Prif Awdur: | |
---|---|
Awduron Eraill: | |
Fformat: | Dissertation |
Iaith: | Saesneg |
Cyhoeddwyd: |
Philipps-Universität Marburg
2009
|
Pynciau: | |
Mynediad Ar-lein: | Testun PDF llawn |
Tagiau: |
Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!
|