Macrocyclization and Fatty Acid Modification during the Synthesis of Nonribosomal Peptides

Macrocyclization and Fatty Acid Modification during the Synthesis of Nonribosomal Peptides

Nonribosomal peptides (NRPs) constitute a large and diverse class of pharmacologically important natural products that find useful therapeutic application as immunosuppressants, antibiotics, or anticancer agents. The biological activity of many of these compounds relies on the macrocyclic structure...

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Dettagli Bibliografici
Autore principale: Kopp, Florian
Altri autori: Marahiel, M. A. (Prof. Dr.) (Relatore della tesi)
Natura: Dissertation
Lingua:inglese
Pubblicazione: Philipps-Universität Marburg 2008
Soggetti:
Peptidsynthetasen
Fettsäuremodifikation
Pepdtidmakrozyklisierung
Lipopeptide Antbiotics
Peptidantibiotikum
Lipopeptidantibiotika
Peptidemacrocyclization
Fatty Acid Modification
Chemie
Nonribosomal Peptide Synthetases
Peptidsynthese
Chemistry & allied sciences
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