The surfactin biosynthetic complex of Bacillus subtilis: COM domain-mediated biocombinatorial synthesis, and single step purification of native multi-modular NRPSs and multi-enzyme complexes

The surfactin biosynthetic complex of Bacillus subtilis: COM domain-mediated biocombinatorial synthesis, and single step purification of native multi-modular NRPSs and multi-enzyme complexes

Most biosynthetic templates for the assembly of peptide natural products are composed of two or more nonribosomal peptide synthetases (NRPSs). For example, the surfactin biosynthetic complex consists of three NRPSs (SrfA-A, SrfA-B, and SrfA-C), which are encoded by the polycistronic srfA operon with...

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Príomhchruthaitheoir: Chiocchini, Claudia
Rannpháirtithe: Buckel, Wolfgang (Prof.) (Comhairleoir tráchtais)
Formáid: Dissertation
Teanga:Béarla
Foilsithe / Cruthaithe: Philipps-Universität Marburg 2006
Ábhair:
Multienzyme complexes
Multienzymkomplex
Biochemistry, molecular biology
COM domains
Protein-protein communication
Biowissenschaften, Biologie
NRPS
COM Domäne
Protein-Protein-Wechselwirkung
Life sciences
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Gairmuimhir: urn:nbn:de:hebis:04-z2006-08381
Dáta a fhoilsithe: 2006-12-21
Datum der Annahme: 2006-06-29
Downloads: 85 (2024), 48 (2023), 49 (2022), 89 (2021), 65 (2020), 71 (2019), 38 (2018)
Lizenz: https://rightsstatements.org/vocab/InC-NC/1.0/
URL Rochtana: https://archiv.ub.uni-marburg.de/diss/z2006/0838
https://doi.org/10.17192/z2006.0838

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