Systematic site-directed mutagenesis to characterize subunit interactions in E. coli asparaginase II, an enzyme

L-asparaginases (EC 3.5.1.1) catalyze the hydrolysis of L-asparagine to aspartic acid and ammonia. Asparaginases of bacterial origin have been used for over 40 years in the treatment of acute lymphatic leukemia (ALL). Asparaginase isoenzyme II from Escherichia coli (EcA2) is especially effective in...

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主要作者: Verma, Shikha
其他作者: Röhm, Klaus-Heinrich (Prof.) (BetreuerIn (Doktorarbeit))
格式: Dissertation
语言:英语
出版: Philipps-Universität Marburg 2005
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索引号: urn:nbn:de:hebis:04-z2005-07051
Publikationsdatum: 2005-12-27
Datum der Annahme: 2005-11-24
Downloads: 47 (2024), 66 (2023), 37 (2022), 50 (2021), 290 (2020), 64 (2019), 26 (2018)
Lizenz: https://rightsstatements.org/vocab/InC-NC/1.0/
访问URL: https://archiv.ub.uni-marburg.de/diss/z2005/0705
https://doi.org/10.17192/z2005.0705