Systematic site-directed mutagenesis to characterize subunit interactions in E. coli asparaginase II, an enzyme

L-asparaginases (EC 3.5.1.1) catalyze the hydrolysis of L-asparagine to aspartic acid and ammonia. Asparaginases of bacterial origin have been used for over 40 years in the treatment of acute lymphatic leukemia (ALL). Asparaginase isoenzyme II from Escherichia coli (EcA2) is especially effective in...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awdur: Verma, Shikha
Awduron Eraill: Röhm, Klaus-Heinrich (Prof.) (Cynghorydd traethodau ymchwil)
Fformat: Dissertation
Iaith:Saesneg
Cyhoeddwyd: Philipps-Universität Marburg 2005
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Manylion daliadau o
Rhif Galw: urn:nbn:de:hebis:04-z2005-07051
Dyddiad Cyhoeddi: 2005-12-27
Datum der Annahme: 2005-11-24
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Lizenz: https://rightsstatements.org/vocab/InC-NC/1.0/
URL mynediad: https://archiv.ub.uni-marburg.de/diss/z2005/0705
https://doi.org/10.17192/z2005.0705