Characterization of PRMT6-dependent splicing during neuronal differentiation of pluripotent NT2/D1 cells

PRMT6-dependent alternative splicing in pluripotent as well as differentiating NT2/D1 cells affects predominantly cassette exons and inton retention in a predominant transcription- and H3R2me2a-independent manner, but relies on PRMT6 enzymatic activity.

Bibliographic Details

Main Author:	Eudenbach, Matthias
Contributors:	Bauer, Uta-Maria (Prof. Dr.) (Thesis advisor)
Format:	Doctoral Thesis
Language:	English
Published:	Philipps-Universität Marburg 2025
Subjects:	neuronal differentiation alternative splicing Medizin PRMT6 Medical sciences Medicine
Online Access:	PDF Full Text
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