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Regulation of Ebola virus transcription by the viral nucleoprotein: Impact of protein interactions and post-translational modifications

The Ebola virus (EBOV) belongs to the family Filoviridae and the order Mononegavirales. Sporadic EBOV outbreaks in sub–Saharan Africa are characterized by a high lethality rate of 40-90%. Replication and transcription of the negative stranded viral genome are facilitated by the viral polymerase L an...

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Main Author: Kämper, Lennart
Contributors: Biedenkopf, Nadine (Dr.) (Thesis advisor)
Format: Doctoral Thesis
Language:English
Published: Philipps-Universität Marburg 2024
Subjects:
post-translational modification
Nucleoprotein
Medizin
Ebola virus
Medical sciences Medicine
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Call Number: urn:nbn:de:hebis:04-z2025-00167
Publication Date: 2025-02-12
Date of Acceptance: 2024-12-13
Downloads: 77 (2025)
License: https://creativecommons.org/licenses/by-nc-nd/4.0/
Access URL: https://archiv.ub.uni-marburg.de/diss/z2025/0016
https://doi.org/10.17192/z2025.0016

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