Regulation of Ebola virus transcription by the viral nucleoprotein: Impact of protein interactions and post-translational modifications

The Ebola virus (EBOV) belongs to the family Filoviridae and the order Mononegavirales. Sporadic EBOV outbreaks in sub–Saharan Africa are characterized by a high lethality rate of 40-90%. Replication and transcription of the negative stranded viral genome are facilitated by the viral polymerase L an...

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Bibliographic Details
Main Author: Kämper, Lennart
Contributors: Biedenkopf, Nadine (Dr.) (Thesis advisor)
Format: Doctoral Thesis
Language:English
Published: Philipps-Universität Marburg 2024
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Online Access:PDF Full Text
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