Elucidating the Role of IgA in Allergic Disease

We uncover an inhibitory role for IgA in mast cell degranulation. We conclude that IgA serves as a regulator of mast cell degranulation, including anaphylaxis, providing a new therapeutic potential for IgE-mediated allergic disease. Additionally, through the development of mice deficient in IgA but...

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Bibliographic Details

Main Author:	El Ansari, Yasmeen
Contributor:	Institute of Laboratory Medicine, Boston Children's Hospital (Issuing body)
Contributors:	Renz, Harald (Prof. Dr.) (Thesis advisor), Oettgen, Hans (Prof.Dr.)
Format:	Doctoral Thesis
Language:	English
Published:	Philipps-Universität Marburg 2024
Subjects:	Atopie IgA-Mangel IgA atopy Allergie IgA deficiency Allgemeines, Wissenschaft Allergy Generalities, Science
Online Access:	PDF Full Text
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