Pharmacological intervention of mitochondrial mechanisms in hemin toxicity and ferroptosis

The growing prevalence of neurological disorders, such as Parkinson's disease, Alzheimer's disease, and strokes, represents a growing challenge for our aging society and is one of the leading causes of morbidity and mortality. These diseases are closely linked to oxidative stress, and inte...

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Bibliographic Details

Main Author:	Merkel, Melanie
Contributors:	Culmsee, Carsten (Prof. Dr.) (Thesis advisor)
Format:	Doctoral Thesis
Language:	English
Published:	Philipps-Universität Marburg 2023
Subjects:	ACSL4 and LPCAT2 over expression selenium compounds LPCAT2 Pharmakologie, Therapeutik Hemin-Toxizität hemin toxicity Hemin Mitochondria Lipid peroxidation ACSL4 Überexpression von ACSL4 und LPCAT2 Selenverbindungen HT22 cells HEK293T cells Ferroptosis Pharmacology & therapeutics, prescription drugs
Online Access:	PDF Full Text
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