Genomics-driven and biochemical approaches to expand the spectrum of natural products

Natural products (NPs) derived from secondary metabolism of living organisms play a pivotal role in drug discovery, especially for the treatment of cancer and infectious diseases. Their versatile skeletons are synthesized by different biosynthetic enzymes including polyketide synthases (PKSs), nonri...

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Bibliographic Details

Main Author:	Li, Wen
Contributors:	Li, Shu-Ming (Prof. Dr.) (Thesis advisor)
Format:	Doctoral Thesis
Language:	English
Published:	Philipps-Universität Marburg 2023
Subjects:	Pharmakologie, Therapeutik prenyltransferases natürliche Produkte Sekundärmetabolite secondary metabolite Penicillium Biosynthese Prenyltransferasen biosynthesis Pharmacology & therapeutics, prescription drugs
Online Access:	PDF Full Text
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