Molecular mechanisms of therapy resistance and recurrence in glioblastoma multiforme

Glioblastoma multiforme (GBM) WHO grade 4 is the most malignant and frequent primary brain tumor with a five-year overall survival rate of 9.8%. Virtually every time, the standard treatment with surgery and radio-/chemotherapy applying temozolomide (TMZ) fails, and the tumor progresses, develops res...

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Bibliographic Details
Main Author: Schäfer, Agnes
Contributors: Bartsch, Jörg-Walter (Prof. Dr.) (Thesis advisor)
Format: Doctoral Thesis
Language:English
Published: Philipps-Universität Marburg 2023
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Online Access:PDF Full Text
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