Molecular mechanisms of therapy resistance and recurrence in glioblastoma multiforme
Glioblastoma multiforme (GBM) WHO grade 4 is the most malignant and frequent primary brain tumor with a five-year overall survival rate of 9.8%. Virtually every time, the standard treatment with surgery and radio-/chemotherapy applying temozolomide (TMZ) fails, and the tumor progresses, develops res...
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Format: | Doctoral Thesis |
Language: | English |
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Philipps-Universität Marburg
2023
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Online Access: | PDF Full Text |
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