Molecular mechanisms of therapy resistance and recurrence in glioblastoma multiforme

Glioblastoma multiforme (GBM) WHO grade 4 is the most malignant and frequent primary brain tumor with a five-year overall survival rate of 9.8%. Virtually every time, the standard treatment with surgery and radio-/chemotherapy applying temozolomide (TMZ) fails, and the tumor progresses, develops res...

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Bibliographic Details
Main Author: Schäfer, Agnes
Contributors: Bartsch, Jörg-Walter (Prof. Dr.) (Thesis advisor)
Format: Doctoral Thesis
Language:English
Published: Philipps-Universität Marburg 2023
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Call Number: urn:nbn:de:hebis:04-z2023-04302
Publication Date: 2023-08-24
Date of Acceptance: 2023-07-10
Downloads: 45 (2024), 43 (2023)
License: https://creativecommons.org/licenses/by-nc-sa/4.0
Access URL: https://archiv.ub.uni-marburg.de/diss/z2023/0430
https://doi.org/10.17192/z2023.0430