Identifizierung funktioneller Untereinheiten des Transkriptionsfaktors interferon regulatory factor 4

Interferon regulatory factor 4 is a crucial factor in adaptive immunity in both T and B cell mediated processes. Knockout mice lacking IRF4 show severe defects in developing functional T cell subsets, including Th2, Th9 and Th17, as well as B cells arrested in early development stages, which l...

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Bibliographic Details

Main Author:	Staudenraus, Daniel
Contributors:	Lohoff, Michael (Prof. Dr.) (Thesis advisor)
Format:	Doctoral Thesis
Language:	English
Published:	Philipps-Universität Marburg 2022
Subjects:	Biowissenschaften, Biologie T-Zelldifferenzierung T cell differentiation Punktmutation Immunologie Differenzierung IRF4 Immunology Life sciences
Online Access:	PDF Full Text
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