Deregulation of signal transduction pathways in macrophages by arachidonic acid in the ovarian cancer microenvironment

Deregulation of signal transduction pathways in macrophages by arachidonic acid in the ovarian cancer microenvironment

Malignant ascites contributes to all hallmarks of ovarian cancer (OC). It occurs as an accumulation of fluid in the peritoneal cavity at advanced stages of the disease. Ascites is associated with a poor prognosis along with a deteriorated quality of life due to abdominal distension. It is now well e...

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Bibliographic Details
Main Author: Hammoud, Mohamad Khir
Contributors: Müller, Rolf (Prof.Dr.) (Thesis advisor)
Format: Doctoral Thesis
Language:English
Published: Philipps-Universität Marburg 2022
Subjects:
Medizin
Macrophages, Tumor microenvironment, Arachidonic acid, TAM, IFNG, IFNB, IL6, Lipid rafts, IL12, ASK1, p38, HSP27, Actin filaments.
Medical sciences Medicine
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Call Number: urn:nbn:de:hebis:04-z2023-01365
Publication Date: 2023-03-09
Date of Acceptance: 2022-11-01
Downloads: 97 (2024), 81 (2023)
License: https://creativecommons.org/licenses/by-nc-sa/4.0
Access URL: https://archiv.ub.uni-marburg.de/diss/z2023/0136
https://doi.org/10.17192/z2023.0136

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