Chromosomal Architecture and its Influence on Gene Expression in Native and Engineered Bacteria

Chromosomal Architecture and its Influence on Gene Expression in Native and Engineered Bacteria

Research in recent years has yielded new insights into the influence of chromosomal architecture at different levels on bacterial gene regulation and expression. On the topological level, chromosome compaction can bring distant genes or regions in spatially proximity, suggesting a regulatory concept...

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Bibliographic Details
Main Author: Teufel, Marc
Contributors: Sobetzko, Patrick (Dr.) (Thesis advisor)
Format: Doctoral Thesis
Language:English
Published: Philipps-Universität Marburg 2022
Subjects:
Kopienzahleffekt
Genom-Editierung
DNA replication
Vibrio natriegens,
Genregulation
Biowissenschaften, Biologie
Gene regulation
CRISPR/Cas9
DNA-Replikation
Genome editing
Copy number effect
Escherichia coli
Vibrio natriegens
Prokaryoten
Gene editing
Bakterien
Dickeya dadantii
Genexpression
Biologie
Gene expression
Biowissenschaften
Life sciences
Online Access:PDF Full Text
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