Elucidation of novel biosynthetic pathways for the discovery of cyclodipeptide derivatives from Streptomyces species

Cyclodipeptides (CDPs) with a 2,5-diketopiperazine (DKP) as central core occur ubiquitously in living organisms, from simple bacteria and fungi to more complex ones like plants and animals. They display various biological and pharmacological effects, including antibiotic, antifungal, and antiprolife...

Full description

Bibliographic Details

Main Author:	Harken, Lauritz Christian
Contributors:	Li, Shu-Ming (Prof. Dr.) (Thesis advisor)
Format:	Doctoral Thesis
Language:	English
Published:	Philipps-Universität Marburg 2022
Subjects:	Fe(II)/2-Oxoglutarate dependent Oxidas Natural Products Biosynthese Cytochrom P-450 Sekundärmetabolit Biosynthesis Fe(II)/2-Oxoglutarat abhängige Oxidase Streptomyces Cyclodipeptidoxidase Cytochrome P450 Pr Cyclodipeptide Oxidase Cyclodipeptidsynthase Pharmakologie, Therapeutik Cyclodipeptide Synthase Pharmacology & therapeutics, prescription drugs
Online Access:	PDF Full Text
Tags:	Add Tag No Tags, Be the first to tag this record!