Characterization of Drosophila Swiprosin-1, a novel conserved actin cross-linking protein, controlling immune cell migration, wound closure and regulated exocytosis

Characterization of Drosophila Swiprosin-1, a novel conserved actin cross-linking protein, controlling immune cell migration, wound closure and regulated exocytosis

Filamentous actin (F-actin) is a dynamic polymer providing mechanical forces to change cell morphology. Calcium is a known modulator of actin cytoskeleton organization, required for many cellular functions including cell migration, wound closure and exocytosis. EFHD2/Swiprosin-1 (Swip-1) is an actin...

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Bibliographic Details
Main Author: Lehne, Franziska
Contributors: Bogdan, Sven (Prof. Dr.) (Thesis advisor)
Format: Doctoral Thesis
Language:English
Published: Philipps-Universität Marburg 2022
Subjects:
calcium
cell migration
Exozytose
Drosphila
Medizin
Kalzium
Aktin
wound healing
cross-linker
exocytosis
actin dynamics
Wundheilung
Zellmigration
Medical sciences Medicine
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Call Number: urn:nbn:de:hebis:04-z2022-03289
Publication Date: 2023-03-09
Date of Acceptance: 2022-08-25
Downloads: 171 (2024), 104 (2023)
License: https://rightsstatements.org/vocab/InC-NC/1.0/
Access URL: https://archiv.ub.uni-marburg.de/diss/z2022/0328
https://doi.org/10.17192/z2022.0328

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