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Genome mining-directed discovery of novel 2,5-diketopiperazines from actinobacteria

Natural products derived from cyclodipeptides (CDPs) with a 2,5-diketopiperazine (DKP) skeleton comprise an important class of secondary metabolites, especially indole alkaloids derived from tryptophan-containing CDPs, which are widespread in fungi, bacteria, and plants. They play vital roles in dru...

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Main Author: Liu, Jing
Contributors: Li, Shu-Ming (Prof. Dr) (Thesis advisor)
Format: Doctoral Thesis
Language:English
Published: Philipps-Universität Marburg 2021
Subjects:
2,5-Diketopiperazine
Actinobakterien
Genome mining
Pharmakologie, Therapeutik
Biosynthesis
Pharmacology & therapeutics, prescription drugs
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Call Number: urn:nbn:de:hebis:04-z2021-01027
Publication Date: 2021-03-31
Date of Acceptance: 2021-03-03
Downloads: 114 (2025), 227 (2024), 183 (2023), 198 (2022), 222 (2021)
License: https://rightsstatements.org/vocab/InC-NC/1.0/
Access URL: https://archiv.ub.uni-marburg.de/diss/z2021/0102
https://doi.org/10.17192/z2021.0102

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