Genome mining-directed discovery of novel 2,5-diketopiperazines from actinobacteria
Natural products derived from cyclodipeptides (CDPs) with a 2,5-diketopiperazine (DKP) skeleton comprise an important class of secondary metabolites, especially indole alkaloids derived from tryptophan-containing CDPs, which are widespread in fungi, bacteria, and plants. They play vital roles in dru...
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