Investigations toward the rational modulation of G protein-coupled receptor signalling pathways using in silico methods

G protein-coupled receptors (GPCRs) are one of the most important protein families and function as signal transducers located in the cell membrane. Currently, about one third of the marketed drugs target a GPCR, reflecting its importance in therapy and disease. Thus, it is not surprising that GPCRs...

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Bibliographic Details
Main Author: Scharf, Magdalena Martina
Contributors: Kolb, Peter (Prof. Dr.) (Thesis advisor)
Format: Doctoral Thesis
Published: Philipps-Universität Marburg 2021
Online Access:PDF Full Text
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