The Power of Fragments: FBLD approach to investigate protein structures

Fragments are small chemical entities with the extraordinary advantage of belonging to a wide variety of functional groups able to explore various chemical spaces, penetrate small protein pockets and allow the mapping of various protein binding sites. Nowadays, fragment-based lead discovery (FBLD) i...

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Bibliographic Details

Main Author:	Magari, Francesca
Contributors:	Klebe, Gerhard (Prof. Dr.) (Thesis advisor)
Format:	Doctoral Thesis
Language:	English
Published:	Philipps-Universität Marburg 2020
Subjects:	96-fragment library fragment-based drug discovery (FBDD) EP Biowissenschaften, Biologie FPPS Fragment screening (FS) TLN Life sciences
Online Access:	PDF Full Text
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