The Power of Fragments: FBLD approach to investigate protein structures

Fragments are small chemical entities with the extraordinary advantage of belonging to a wide variety of functional groups able to explore various chemical spaces, penetrate small protein pockets and allow the mapping of various protein binding sites. Nowadays, fragment-based lead discovery (FBLD) i...

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Bibliographic Details
Main Author: Magari, Francesca
Contributors: Klebe, Gerhard (Prof. Dr.) (Thesis advisor)
Format: Doctoral Thesis
Published: Philipps-Universität Marburg 2020
Online Access:PDF Full Text
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