The Power of Fragments: FBLD approach to investigate protein structures

Fragments are small chemical entities with the extraordinary advantage of belonging to a wide variety of functional groups able to explore various chemical spaces, penetrate small protein pockets and allow the mapping of various protein binding sites. Nowadays, fragment-based lead discovery (FBLD) i...

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Bibliographic Details
Main Author: Magari, Francesca
Contributors: Klebe, Gerhard (Prof. Dr.) (Thesis advisor)
Format: Doctoral Thesis
Language:English
Published: Philipps-Universität Marburg 2020
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Call Number: urn:nbn:de:hebis:04-z2020-02145
Publication Date: 2020-05-25
Date of Acceptance: 2020-02-25
Downloads: 92 (2024), 208 (2023), 185 (2022), 163 (2021), 65 (2020)
License: https://creativecommons.org/licenses/by-nc-nd/4.0/
Access URL: https://archiv.ub.uni-marburg.de/diss/z2020/0214
https://doi.org/10.17192/z2020.0214