Thermodynamic, Kinetic and Crystallographic Investigations of Benzenesulfonamides as Ligands of Human Carbonic Anhydrase II

The data presented here show that different geometries of para-alkyl substituents of a benzenesulfonamide scaffold can have a significant influence on the thermodynamic and kinetic binding parameters and suggest, that the fine-tuning of the ligand geometry to match the geometry of the active site le...

Full description

Saved in:
Bibliographic Details
Main Author: Glöckner, Steffen
Contributors: Klebe, Gerhard Prof. Dr. (Thesis advisor)
Format: Doctoral Thesis
Published: Philipps-Universität Marburg 2020
Online Access:PDF Full Text
Tags: Add Tag
No Tags, Be the first to tag this record!


PDF Full Text

Holdings details from
Call Number: urn:nbn:de:hebis:04-z2020-01231
Publication Date: 2020-12-22
Date of Acceptance: 2020-02-14
Downloads: 121 (2024), 159 (2023), 91 (2022), 55 (2021), 9 (2020)
Access URL: