The role of the actin-binding proteins cofilin1 and INF2 on mitochondrial dynamics and cellular resilience

Neurological diseases, such as stroke, Alzheimer’s disease and related dementias are among the most prevalent disorders leading to disability and death worldwide. Many cell death pathways, including apoptosis, necrosis and necroptosis, oxytosis or ferroptosis, relevant for these pathologies, converg...

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Bibliographic Details

Main Author:	Hoffmann, Lena
Contributors:	Culmsee, Carsten (Prof. Dr.) (Thesis advisor)
Format:	Doctoral Thesis
Language:	English
Published:	Philipps-Universität Marburg 2020
Subjects:	Ferroptose cell death excitotoxicity actin-binding proteins ferroptosis mitochondrial dynamics neuronaler Zelltod Exzitotoxizität oxytosis Pharmakologie, Therapeutik Neurone mitochondriale Funktion mitochondrial function Aktin-bindende Proteine Oxytose mitochondriale Dynamik Zelltod Pharmacology & therapeutics, prescription drugs
Online Access:	PDF Full Text
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