Lipodendriplexes: A promising nanocarrier for enhanced nucleic acid delivery

Lipodendriplexes: A promising nanocarrier for enhanced nucleic acid delivery

The main objective of the current study was to developed an optimized system for enhanced nucleic acid delivery with minimum cytotoxicity. For efficient therapeutic gene delivery, PAMAM dendrimer, with ethylenediamine core was chosen due to its biodegradable and non-immunogenic nature. However, the...

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Bibliographic Details
Main Author: Tariq, Imran
Contributors: Bakowsky, Udo (Prof. Dr.) (Thesis advisor)
Format: Doctoral Thesis
Language:English
Published: Philipps-Universität Marburg 2019
Subjects:
siRNA
3D-Bioprinting
Ex vivo
Zyto
Gentherapie
Herunterregulierung
Gene therapy
In vivo
Plasmid DNA
Lipodendriplexe
Apoptose
Plasmid-DNA
Cytot
Dendriplexe
PAMAM
Lipodendriplexes
Pharmakologie, Therapeutik
Liposomen
Liposomes
Downregulation
Apoptosis
3D bioprinting
Dendriplexes
Pharmacology & therapeutics, prescription drugs
Online Access:PDF Full Text
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