Selective cellular vulnerability and pathology progression patterns in two mouse models of Parkinson’s disease

Parkinson's disease is a highly debilitating disorder classically characterized by the degeneration of dopaminergic midbrain neurons of the substantia nigra. The resulting nigrostriatal dopamine deficiency is thought to be responsible for the onset of the cardinal Parkinson's motor symptom...

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Bibliographic Details

Main Author:	Geibl, Fanni Fruzsina
Contributors:	Oertel, Wolfgang H. (Prof. Dr. med. Dr. h.c.) (Thesis advisor)
Format:	Doctoral Thesis
Language:	English
Published:	Philipps-Universität Marburg 2019
Subjects:	selective vulnerab preformed fibrils Medizin adeno-associated viral vectors Locus coeruleus präformierte Fibrillen Pedunculopontiner Kern pedunculopontine nucleus alpha-Synuclein selektive Vulnerabilit adeno-assoziierte Viren Parkinson's disease Parkinson-Krankheit alpha-synuclein Medical sciences Medicine
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