Publikationsserver
Synthetic lethal interactions between ATR and DNA polymerases as a novel concept for individualized cancer therapy
The chemical inhibition of the kinase ATR, a central regulator of the DNA damage response, eliminates subsets of cancer cells in different tumors. This effect is at least partly attributable to the synthetic lethal relationship between ATR and certain DNA repair genes. In a previous study of our lab...
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| Format: | Dissertation |
| Sprache: | Englisch |
| Veröffentlicht: |
Philipps-Universität Marburg
2019
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| Online Zugang: | PDF-Volltext |
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