Directed Evolution of an Fe(II)-Dependent Halogenase for Asymmetric C(sp3)-H Chlorination
Within this thesis, the chlorinase Wi-WelO15 from Westiella intricata UH strain HT-29-1 was explored for its evolvability towards non-natural substrates and its biocatalytic applicability. Organohalogens play an important role as pharmaceuticals and agricultural chemicals or synthetic intermediat...
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