Elucidating the functional role of Dual-specificity Tyrosine Regulated Kinase 1B (DYRK1B) in the Hedgehog (Hh) Signaling Pathway.

Hedgehog signaling (Hh) plays a crucial role in vital processes such as embryonic development or cell homeostasis. Aberrant Hh signaling is linked to formation, progression, and growth of tumors. The canonical Hh signaling cascade is initiated by binding of the Hh ligand to its receptor Patched1...

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Bibliographic Details
Main Author: Singh, Rajeev
Contributors: Lauth, Matthias (PD Dr.) (Thesis advisor)
Format: Doctoral Thesis
Published: Philipps-Universität Marburg 2018
Online Access:PDF Full Text
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