Dimethyl fumarate suppresses Tc17 cell fate in autoimmunity via ROS accumulation

Dimethyl fumarate (DMF) is approved for treatment of relapsing remitting multiple sclerosis (RRMS), a chronic inflammatory disease of the central nervous system (CNS) that is caused by autoreactive T cells. The effect mechanism of DMF is not fully elucidated so far; however, a preferential impact on...

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Bibliographic Details

Main Author:	Lückel, Christina
Contributors:	Huber, Magdalena (Prof. Dr.) (Thesis advisor)
Format:	Doctoral Thesis
Language:	English
Published:	Philipps-Universität Marburg 2018
Subjects:	ROS Multiple Sklerose Tc17 cells IL-17 Dimethyl fumarate Dimethylfumarat multiple sclerosis Medizin Tc17 Zellen Medical sciences Medicine
Online Access:	PDF Full Text
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