Dimethyl fumarate suppresses Tc17 cell fate in autoimmunity via ROS accumulation

Dimethyl fumarate (DMF) is approved for treatment of relapsing remitting multiple sclerosis (RRMS), a chronic inflammatory disease of the central nervous system (CNS) that is caused by autoreactive T cells. The effect mechanism of DMF is not fully elucidated so far; however, a preferential impact on...

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Bibliographic Details
Main Author: Lückel, Christina
Contributors: Huber, Magdalena (Prof. Dr.) (Thesis advisor)
Format: Doctoral Thesis
Language:English
Published: Philipps-Universität Marburg 2018
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Call Number: urn:nbn:de:hebis:04-z2018-03301
Publication Date: 2019-02-28
Date of Acceptance: 2018-08-15
Downloads: 66 (2024), 86 (2023), 69 (2022), 72 (2021), 76 (2020), 69 (2019)
License: https://creativecommons.org/licenses/by-nc-sa/4.0
Access URL: https://archiv.ub.uni-marburg.de/diss/z2018/0330
https://doi.org/10.17192/z2018.0330