Functional characterisation of cancer-associated mutations in the chromatin remodeler CHD4/dMi-2

CHD4/Mi-2 is a highly conserved ATP-dependent chromatin remodeller. It is essential in processes like transcription regulation, DNA damage response, cell cycle progression, as well as differentiation and development in eukaryotes. It is one of the catalytic components of the NuRD (nucleosome remodel...

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Bibliographic Details
Main Author: Kovač, Kristina
Contributors: Brehm, Alexander, (Prof. Dr.) (Thesis advisor)
Format: Dissertation
Language:English
Published: Philipps-Universität Marburg 2018
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Online Access:PDF Full Text
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