Functional characterisation of cancer-associated mutations in the chromatin remodeler CHD4/dMi-2

Functional characterisation of cancer-associated mutations in the chromatin remodeler CHD4/dMi-2

CHD4/Mi-2 is a highly conserved ATP-dependent chromatin remodeller. It is essential in processes like transcription regulation, DNA damage response, cell cycle progression, as well as differentiation and development in eukaryotes. It is one of the catalytic components of the NuRD (nucleosome remodel...

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Bibliographic Details
Main Author: Kovač, Kristina
Contributors: Brehm, Alexander, (Prof. Dr.) (Thesis advisor)
Format: Doctoral Thesis
Language:English
Published: Philipps-Universität Marburg 2018
Subjects:
tumour
Nukleosom
endometrium
Tumor
Gebärmutterschleimhaut
mutation
Chromatin
Mutation
nucleosome
CHD4
Medizin
chromatin
Mutation, CHD4, Chromatin-Remodellierung
Histone
chromatin remodelling
Medical sciences Medicine
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Call Number: urn:nbn:de:hebis:04-z2018-02561
Publication Date: 2018-06-04
Date of Acceptance: 2018-04-24
Downloads: 49 (2023), 87 (2022), 69 (2021), 67 (2020), 44 (2019), 62 (2018)
License: https://creativecommons.org/licenses/by-nc-sa/4.0
Access URL: https://archiv.ub.uni-marburg.de/diss/z2018/0256
https://doi.org/10.17192/z2018.0256

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