Opposing activities of IRF1 and IRF4 in regulating the Il9 locus in Th9 cells

The T helper (Th)9 cell transcriptional network is formed by an equilibrium of signals induced by cytokines and antigen presentation. Positive regulators including interferon regulatory factor (IRF)4 promote expression of the key cytokine interleukin (IL)-9 in Th9 cells, whereas interferon (IFN)-γ r...

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Bibliographic Details
Main Author: Campos Carrascosa, Lucia
Contributors: Huber, Magdalena (Prof. Dr.) (Thesis advisor)
Format: Doctoral Thesis
Language:English
Published: Philipps-Universität Marburg 2017
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Online Access:PDF Full Text
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