Opposing activities of IRF1 and IRF4 in regulating the Il9 locus in Th9 cells

Opposing activities of IRF1 and IRF4 in regulating the Il9 locus in Th9 cells

The T helper (Th)9 cell transcriptional network is formed by an equilibrium of signals induced by cytokines and antigen presentation. Positive regulators including interferon regulatory factor (IRF)4 promote expression of the key cytokine interleukin (IL)-9 in Th9 cells, whereas interferon (IFN)-γ r...

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Bibliographic Details
Main Author: Campos Carrascosa, Lucia
Contributors: Huber, Magdalena (Prof. Dr.) (Thesis advisor)
Format: Doctoral Thesis
Language:English
Published: Philipps-Universität Marburg 2017
Subjects:
Th9-Zellen
IRF4
IRF1
Medizin
Th9 cells
Il9-Locus
Il9 locus
Medical sciences Medicine
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Call Number: urn:nbn:de:hebis:04-z2017-05981
Publication Date: 2017-10-25
Source: https://www.nature.com/articles/ncomms15366
Date of Acceptance: 2017-10-16
Downloads: 71 (2024), 61 (2023), 47 (2022), 35 (2021), 25 (2020), 21 (2019), 25 (2018)
License: https://creativecommons.org/licenses/by-nc-sa/4.0
Access URL: https://archiv.ub.uni-marburg.de/diss/z2017/0598
https://doi.org/10.17192/z2017.0598

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