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Beyond Affinity: Drug-Kinase Interaction Put under the Microscope
Over the last 20 years, the consideration of biophysical parameters such as kinetics and thermodynamics has been used to guide modern drug design. In contrast to the classical approach that mainly relies on affinity optimization, biophysical parameters allow a further discrimination of potential dru...
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| Main Author: | |
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| Contributors: | |
| Format: | Doctoral Thesis |
| Language: | English |
| Published: |
Philipps-Universität Marburg
2017
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| Subjects: | |
| Online Access: | PDF Full Text |
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Internet
PDF Full Text| Call Number: |
urn:nbn:de:hebis:04-z2017-05379 |
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| Publication Date: |
2018-04-05 |
| Date of Acceptance: |
2017-06-12 |
| Downloads: |
145 (2024), 97 (2023), 38 (2022), 13 (2021), 17 (2020), 24 (2019), 17 (2018) |
| License: |
https://creativecommons.org/licenses/by-nc-sa/4.0 |
| Access URL: |
https://archiv.ub.uni-marburg.de/diss/z2017/0537 https://doi.org/10.17192/z2017.0537 |