IL-17 and TNF-alpha are essential mediators of M. catarrhalis triggered exacerbation of HDM allergic airway inflammation

In this study we have demonstrated in a murine model of allergic airway inflammation that intranasal infection with the human pathogen M. catarrhalis exacerbate pulmonary inflammation. The aim of the study was: i) to establish an animal model of infection induced exacerbation of lung allergic re...

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Bibliographic Details
Main Author: Alnahas, Safa
Contributors: Steinhoff, Ulrich (Prof. Dr.) (Thesis advisor)
Format: Doctoral Thesis
Language:English
Published: Philipps-Universität Marburg 2017
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Call Number: urn:nbn:de:hebis:04-z2017-03955
Publication Date: 2017-07-13
Date of Acceptance: 2017-05-16
Downloads: 72 (2024), 81 (2023), 70 (2022), 46 (2021), 24 (2020), 20 (2019), 19 (2018)
License: https://creativecommons.org/licenses/by-nc-sa/4.0
Access URL: https://archiv.ub.uni-marburg.de/diss/z2017/0395
https://doi.org/10.17192/z2017.0395