The species-specific effects of guinea pig adaptive mutations in Marburg virus VP40 and L on the protein’s functions and viral fitness

Marburg virus (MARV) is a highly pathogenic virus that causes severe, often lethal diseases specifically in humans and non-human primates. In rodents MARV is non-pathogenic. However, sequential passaging of MARV in rodents results in selection of a rodent-lethal virus. Lofts et al. established a gui...

Full description

Saved in:
Bibliographic Details
Main Author: Köhler, Alexander
Contributors: Becker, Stephan (Prof. Dr.) (Thesis advisor)
Format: Doctoral Thesis
Published: Philipps-Universität Marburg 2017
Online Access:PDF Full Text
Tags: Add Tag
No Tags, Be the first to tag this record!


PDF Full Text

Holdings details from
Call Number: urn:nbn:de:hebis:04-z2017-03377
Publication Date: 2017-06-12
Date of Acceptance: 2017-05-10
Downloads: 71 (2024), 106 (2023), 97 (2022), 109 (2021), 122 (2020), 112 (2019), 40 (2018)
Access URL: