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Establishment and characterization of preclinical mouse models for evaluation of oncogenic and tumor-suppressive properties of p53 family members

Cancer development is a multistep process which leads to tumors composed of diverse cell populations originating from one cell which underwent differential genetic changes over time. Within one tumor, such heterogeneity provides distinct subpopulations with selection advantages promoting metastasis...

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Main Author: Fuchs, Jeannette
Contributors: Stiewe, Thorsten (Prof. Dr.) (Thesis advisor)
Format: Doctoral Thesis
Language:English
Published: Philipps-Universität Marburg 2016
Subjects:
Biowissenschaften, Biologie
p53 p73 Tumorbiologie
p53 p73 tumor biology
Life sciences
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Call Number: urn:nbn:de:hebis:04-z2017-02859
Publication Date: 2017-04-27
Date of Acceptance: 2017-03-22
Downloads: 21 (2025), 120 (2024), 89 (2023), 68 (2022), 60 (2021), 70 (2020), 67 (2019), 7 (2018)
License: https://creativecommons.org/licenses/by-nc-sa/4.0
Access URL: https://archiv.ub.uni-marburg.de/diss/z2017/0285
https://doi.org/10.17192/z2017.0285

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