Characterization of cellular and humoral immune responses in pemphigus patients and an HLA-transgenic mouse model

The rare, but potentially fatal autoimmune disorder pemphigus is considered as a prototypical antibody-mediated organ-specific disease, in which immunoglobulin (Ig) G autoantibodies (auto-ab) mainly target the desmosomal cadherins Desmoglein 3 (Dsg3) and Dsg1 within the epidermis. This process, refe...

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Bibliographic Details

Main Author:	Hennerici, Tina
Contributors:	Eming, Rüdiger (PD Dr.) (Thesis advisor)
Format:	Doctoral Thesis
Language:	English
Published:	Philipps-Universität Marburg 2016
Subjects:	Autoimmunität Antikörper Autoantibodies Autoantikörper Medizin Autoimmunity Medical sciences Medicine
Online Access:	PDF Full Text
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