Selective targeting of immunoproteasome subunit LMP7 prevents colitis-associated carcinogenesis
Chronic inflammation is a well-known risk factor for the development of colonic tumorigenesis. In this study, we show that the immunoproteasome (iP) subunit LMP7 plays a crucial role in the progression of colitis-associated carcinogenesis (CAC). The activity and function of the iP complex has been e...
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Format: | Dissertation |
Sprache: | Englisch |
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Philipps-Universität Marburg
2016
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