Towards Bioorthogonal Enzymatic Uncaging Reactions

In this thesis, engineered cytochrome P450 monooxygenase mutants are reported as highly active and selective catalysts for the bioorthogonal uncaging of diferent ether protected substrates, including the successful transfer of the uncaging reaction into living bacteria. This proof-of-principle study...

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Bibliographic Details
Main Author: Ritter, Cornelia
Contributors: Meggers, Eric (Prof. Dr.) (Thesis advisor)
Format: Doctoral Thesis
Published: Philipps-Universität Marburg 2016
Online Access:PDF Full Text
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