Functional Characterization of the BCR/JAK2 Fusion Gene in a Murine Pro B Cell Line

Functional description of the BCR/JAK2 fusion gene, which has been described in a patient suffering from chronic myeloid leukaemia in 2005. The T(translocation)(9;22)(p24;q11.2)leads to the formation of a fusion gene which incorporates critical regions of the breakpoint cluster region- as well as th...

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Bibliographic Details

Main Author:	Marbach, Felix
Contributors:	Bohlander, Stefan (Prof. Dr.) (Thesis advisor)
Format:	Doctoral Thesis
Language:	English
Published:	Philipps-Universität Marburg 2015
Subjects:	Translokation Fusion gene Leukämie Medical applications (general) Tumor Klonierung Protein-Tyrosin-Kinasen Tyrosinkinase-Inhibitor Medizin Onkogen Mutation Fusionsgen Tyrosine kinase inhibitor Medical sciences Medicine
Online Access:	PDF Full Text
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