La Crosse virus NSs sequesters Elongin C - a possible mechanism for inducingdegradation of the largest subunit of RNA polymerase II

Viruses in the Bunyaviridae family cause disease in humans ranging from a mild transient fever to viral haemorrhagic fever. The orthobunyavirus genus is the largest within the family and contains the La Crosse virus (LACV). LACV is endemic in the USA, causing 85 % of neuroinvasive viral disease in c...

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Bibliographic Details
Main Author: Schön, Andreas
Contributors: Weber, Friedemann, (Prof. Dr.) (Thesis advisor)
Format: Doctoral Thesis
Language:English
Published: Philipps-Universität Marburg 2015
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Call Number: urn:nbn:de:hebis:04-z2015-05701
Publication Date: 2015-10-21
Date of Acceptance: 2015-10-16
Downloads: 24 (2024), 59 (2023), 60 (2022), 32 (2021), 30 (2020), 32 (2019), 18 (2018)
License: https://creativecommons.org/licenses/by-nc-sa/4.0
Access URL: https://archiv.ub.uni-marburg.de/diss/z2015/0570
https://doi.org/10.17192/z2015.0570