Inhibitors of p53 and HIF-prolyl-4-hydroxylases provide mitochondrial protection in a model of oxytosis

Mitochondrial dysfunction and demise are hallmarks of many neurological disorders and neurodegenerative diseases. Since mitochondria are the key organelles providing energy, they are regarded as the power house of the cell. Under conditions of stress, mitochondria regulate the ‘point of no return’...

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Bibliographic Details
Main Author: Neitemeier, Sandra
Contributors: Culmsee, Carsten (Prof. Dr.) (Thesis advisor)
Format: Doctoral Thesis
Language:English
Published: Philipps-Universität Marburg 2015
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Call Number: urn:nbn:de:hebis:04-z2015-03549
Publication Date: 2016-01-25
Date of Acceptance: 2015-06-24
Downloads: 48 (2024), 72 (2023), 55 (2022), 81 (2021), 93 (2020), 219 (2019), 90 (2018)
License: https://rightsstatements.org/vocab/InC-NC/1.0/
Access URL: https://archiv.ub.uni-marburg.de/diss/z2015/0354
https://doi.org/10.17192/z2015.0354