Inhibitors of p53 and HIF-prolyl-4-hydroxylases provide mitochondrial protection in a model of oxytosis

Mitochondrial dysfunction and demise are hallmarks of many neurological disorders and neurodegenerative diseases. Since mitochondria are the key organelles providing energy, they are regarded as the power house of the cell. Under conditions of stress, mitochondria regulate the ‘point of no return’...

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Bibliographic Details

Main Author:	Neitemeier, Sandra
Contributors:	Culmsee, Carsten (Prof. Dr.) (Thesis advisor)
Format:	Doctoral Thesis
Language:	English
Published:	Philipps-Universität Marburg 2015
Subjects:	Zelltod Mitochondrium oxytosis neuronal cell death p53 Protein p53 Oxidativer Stress HIF-prolyl-4-hydroxylase Medizin mitochondria Medical sciences Medicine
Online Access:	PDF Full Text
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