An extracellular drug binding site of potassium channels THIK-1 and THIK-2

Background: THIK-1, THIK-2 and TREK-1 and all belong to family of two-pore-domain potassium channel (K2P channels). THIK-2 was until recently regarded as ‘silent’ potassium channels. 3-isobutyl-1-methylxanthine (IBMX) is normally used as inhibitor of phosphodiesterase, resulting in an increase of cA...

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Bibliographic Details

Main Author:	Zou, Xinle
Contributors:	Daut, Jürgen (Prof. Dr.) (Thesis advisor)
Format:	Doctoral Thesis
Language:	English
Published:	Philipps-Universität Marburg 2015
Subjects:	Kalium Medizin IBMX Kanal Kanal, IBMX, THIK potassium channel Medical sciences Medicine
Online Access:	PDF Full Text
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