Polymerase mutations promoting adaptation of avian influenza virus of subtype H9N2 to mammals

Transmission of influenza viruses from aquatic birds to mammals is promoted by the adaptation of the viral proteins to the new host. This includes the PB2 subunit of the viral polymerase complex. This protein has been described as an important host range factor, able to modulate the virulence of inf...

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Bibliographic Details

Main Author:	Sediri, Hanna
Contributors:	Klenk, Hans-Dieter (Prof. Dr.) (Thesis advisor)
Format:	Doctoral Thesis
Language:	English
Published:	Philipps-Universität Marburg 2015
Subjects:	Medizin Influenza-A-Virus Influenza-A-Viren polymerase complex Adaptation Polymerasekomplex Grippe mutations adaptation Anpassung Viren Säugetiere Mutation Mutationen Medical sciences Medicine
Online Access:	PDF Full Text
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