Genome Mining, Isolation and Characterization of Novel Lasso Peptides and Their Utilization in Drug Development

Lasso peptides are a class of natural products that belong to the family of ribosomally‑assembled and posttranslationally‑modified peptides. They are defined by an unique structural motif referred to as the so‑called lariat knot, whose name is derived from the fact that this topology is reminiscent...

Full description

Bibliographic Details

Main Author:	Hegemann, Julian David
Contributors:	Marahiel, Mohamed A. (Prof. Dr.) (Thesis advisor)
Format:	Doctoral Thesis
Language:	English
Published:	Philipps-Universität Marburg 2014
Subjects:	Epitope Grafting ribosomal synthetisierte Naturstoffe Strukturaufklärung Naturstoffchemie ribosomally-assembled natural products lasso peptide Biosynthese RIPPs Naturstoff Chemie Peptide drug development epitope grafting Biochemie Wirkstoffentwicklung Lassopeptide Chemistry & allied sciences
Online Access:	PDF Full Text
Tags:	Add Tag No Tags, Be the first to tag this record!